Cortical Dynein and Asymmetric Membrane Elongation Coordinately Position the Spindle in Anaphase
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چکیده
منابع مشابه
Cortical Dynein and Asymmetric Membrane Elongation Coordinately Position the Spindle in Anaphase
Mitotic spindle position defines the cell-cleavage site during cytokinesis. However, the mechanisms that control spindle positioning to generate equal-sized daughter cells remain poorly understood. Here, we demonstrate that two mechanisms act coordinately to center the spindle during anaphase in symmetrically dividing human cells. First, the spindle is positioned directly by the microtubule-bas...
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ژورنال
عنوان ژورنال: Cell
سال: 2013
ISSN: 0092-8674
DOI: 10.1016/j.cell.2013.06.010